Adult stem cells research

Stem Cell Research
Alomac® – Dried Aloe macroclada gel (vahona)

Alomac is a unique aloe, found only in Madagascar, and shown to upregulate the stem cells in the body better than any other natural product and without the toxicity of unnatural products.

Drapeau, C, Benson, K.F, James. J, and Jensen, G.S. (2015) Aloe macroclada from Madagascar Triggers Transient Bone Marrow Stem Cell Mobilization, Journal of Stem Cell Research & Therapy, 5:6, DOI: 10.4172/2157-7633.1000287

  • Objective: Aloe has been used for the treatments of various ailments dating back almost 6000 years. There are more than 450 species of aloe coming from various parts of Africa and South America, and from the island of Madagascar that contains unique species endemic to the island. One such species is Aloe macroclada that has been used for centuries by the local residents as a remedy for a wide variety of ailments. We investigated whether the mechanism of action behind the wide-ranging health benefits of A. macroclada could be mobilization of bone marrow stem cells.
  • Methods: A. macroclada was prepared into small spherical pellets by Malagasy healers using traditional methods of fabrication. The traditional dose of three pellets was fed to 4 volunteers and the number of circulating stem cells was quantified 1, 2 and 3 hours after consumption using flow-cytometry.
  • Results: The usual dose and preparation of A. macroclada traditionally used in Madagascar triggered a significant increase (up to 53%) in the number of circulating CD45dim CD34+ and CD34+ CD133+ stem cells within 2 hours of consumption. This increase lasted more than 3 hours and was significant after 120 and 180 minutes of consumption.

Conclusion: Consumption of A. macroclada has been credited with significant improvements in a wide variety of heath conditions. This data suggest that stem cell mobilization may be an important mechanism of action behind the health benefits of A. macroclada.

Following this positive study with healer-made pellets (calculated to contain 70-100mg A. macroclada gel), additional clinical studies were performed on the pure A. macroclada gel powder. Subjects were dosed at 250 and 750mg and samples were taken to monitor stem cell concentrations similarly to the first study. These studies have not yet been published, however some preliminary data is available at this time. The two following graphs show the average CD34+CD133 cell counts over time for each dose group and the maximum level with standard error of mean within the group.

John W. James, Owner and General Manager
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